The Nobel prize in Physiology or Medicine 2018 goes to James P. Allison and Tasuku Honjo. The hard work of both of them got him Nobel Prize 2018 medicine.
James P. Allison and Tasuku Honjo got the Noble prize of 2018 in Physiology or Medicine. They both contribute 26 years of their life in the research of treatment of Cancer.
They both discovered a protein and vitamin which can heal the human body with cancer without any side effect and reaction.
Nobel Prize Winners Of 2018 In Medicine Or Physiology
James P. Allison is from the University of Texas. He is an American physiologist. James has to spend 1/3 part of his life in studying about Cancer Immunotherapy.
He devotes his 26 years of his life in the research and he teaches us a lesson of hard work. In the time period of 26 years, he had failed many times but his continuous efforts lead him to the Nobel prize.
James told in his interview after winning the prize that he can’t succeed in his aim without his companions.
Dr. Tasuku Honjo is from the University of Kyoto. He is a Japanese physiologist. He also observed the same things that James P. Allison found.
He also studied the self immunotherapy in the human body. He observed that the human body have the potential to fight against the cancer tissue but for some protein, this system is on hold.
What Is Cancer Immunotherapy
First, we have to know what is cancer? Cancer is a very dangerous disease. Cancer cells enter our body and damaging all our internal parts slowly. That is why you can not tell any person that he is suffering from cancer from his physical appearance.
Cancer is of different types like Breast cancer, Prostate cancer, Basel cell cancer, Skin cancer, Lungs cancer, blood cancer, Lymphomacancer and many other types of cancer.
Second, we have to know that what is Immunotherapy? A human body has a very good ability to heal itself from any disease. The ability of our body to kill other cells of different types which can harm our body is known as Immunity power.
James P. Allison And Tasuku Honjo Discory On Immunotherapy
James P. Allison and Tasuku Honjo deeply studied on the Immunotherapy of cancer and then they noticed that.
When cancer cells enter in our body they are is in very small quantity but they are fully uncontrolled. After entering they can multiply themselves and form a cancer membrane in our body.
This cancer membrane can effect in our body. In some cases, this membrane is transferred to different parts of our body. This case is generally found in Blood cancer and Lungs cancer.
But he discovered that in our body a cell is found and his work is to destroy all the different cells in our body which are harmful to our body. These cells are called T-cells.
But the problem is that T-cells stop destroying other cells due to feedback machines in our body. The feedback machines send the signal to stop attacking other cells.
Efforts Of Noble Prize Winners In Creating Anti Protein
But the problem is that a special type of protein is found on the outer part of T-cells which stops him to attack cancer cells and other cells. These proteins are CTLA-4 and PD-1.
James P. Allison discovered CTLA-4 protein and Tasuku Honjo discovered PD-1.
So both the Nobel prize winners 2018 research on how to remove CTLA-4 and PD-1 so that the T-cell can work properly and kill the cancer cell.
Because of their continuous efforts and hard work, they both succeed in making Anti CTLA-4 (ipilimumab) and Anti PD-1 (pembrolizumab nivolumab).
The problem of cancer is solved. If we give anti proteins to any person who is suffering from cancer then these proteins can clear the path of T-cells.
So that T-cells can kill cancer cells continuously and the patient becomes well. These are the good works of both the scientists which leads them to the Noble prize of 2018. Also get some Writing Views On this topic.