Can mixing two COVID vaccine doses boost immune response?


Recently, Dr NK Arora, chairman of the central authorities’s COVID-19 working group mentioned that specialists could begin testing to see if mixing doses of two completely different COVID vaccines might boost immune response.

The authorities, nonetheless, went to make clear thereafter that there can be no mixing of vaccine doses.

Meanwhile, researchers all over the world have been finding out the results of mixing COVID vaccine doses. A examine in Spain, led by the Carlos III Health Institute in Madrid, present in its preliminary trial that vaccinating individuals with each Oxford–AstraZeneca and Pfizer–BioNTech COVID-19 might produce a potent immune response.

A UK examine known as Com-COV discovered that individuals within the mix-and-match teams had gentle to reasonable frequent vaccine-related unwanted effects than those that acquired two doses of the identical vaccine.

Countries like Canada, France, Norway, and Sweden, amongst others, have beneficial mixing vaccine doses as another international locations proceed testing.

The technique is named heterologous prime-boost COVID-19 vaccination, and adopted to mitigate “supply shocks or shortages that might otherwise reduce the speed of vaccine roll-out,” in accordance with a examine revealed by The Lancet in May.

Whether one can obtain two completely different doses of the COVID vaccine can solely be decided by intensive analysis, mentioned Dr Vikas Maurya, head of division and director, pulmonology, Fortis Hospital, Shalimar Bagh. “Researchers are already studying the effects of mixing the vaccine shots. Further research is required to understanding if doing this will boost the immune response or reduce it. For now, what we can say is a Covaxin shot should be followed by a booster dose of Covaxin only; the same applies for Covishield,” he added.

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